Use of Probiotics Antibiotic-induced Diarrhea Reduces Riskin

In a review conducted in the Cochrane Library based on the results of previous studies, probiotic food supplements or probiotic-containing foods were found to be effective in preventing diarrhea caused by the use of antibiotics.

Researchers say that probiotics taken with antibiotics may be effective in preventing some of the adverse effects that antibiotic use can cause.

As is known, antibiotics cause the death of beneficial bacteria living in the intestines and forming the intestinal flora. For this reason, some bacteria such as C. difficile can multiply in the intestines and cause diarrhea. However, while some people with intestinal bacteria such as C. difficile are not affected by this condition, some people can develop diseases such as diarrhea or colitis.


Probiotics containing beneficial bacteria that contribute to the structure of the intestinal flora or the yeast found in probiotic foods are both a safe and economical alternative to the prevention of diarrhea caused by C. difficile. Experts emphasize that this reconnaissance is important because treatment with C. difficile diarrhea can be a costly treatment.

In a study published in JAMA, it has been mentioned that the consumption of probiotic foods such as yoghurt can be very useful in preventing antibiotic use of diarrhea origin.

The researchers examined the results of 23 clinical trials involving 4213 adults and children who had diarrhea caused by C. difficile due to antibiotic use. As a result, only 2% of the patients fed probiotics had C. difficile-induced diarrhea, while 6% of the placebo-treated group (control group without probiotics) had diarrhea due to C. difficile. In addition, many side effects due to antibiotics were observed in the placebo group that did not use probiotics, but these side effects were significantly less in the probiotic group.

"In the short term, probiotic foods taken with antibiotics are a simple and effective way of preventing diarrhea caused by C. difficile," said Bradley Johnston, principal investigator at the Hospital for Sick Children Research Institute. "Probiotics taken with antibiotics are very fast acting We are continuing our research on probiotic doses that need to be taken to achieve the best effect, and we can say that probiotics cause C. difficile infection to have a therapeutic effect on the symptoms of this infection instead of treating it. "